So you have an action-packed manga with a lot of stuff going on. That's cool.
You can play around with your page layout, sound words and speech bubbles, but here's one thing you can never, ever do: Mess with the reading flow.
For the most part, there are only two ways to read a manga: left to right, top to bottom and right to left, top to bottom.
Once you've chosen either one, it must be applied consistently.
When layouting your manga page, be aware of what the focal points are; Usually these are things such as speech bubbles, sound words, the characters faces and sometimes certain objects.
The focal points must always offer a clear path for the eye of the reader. Generally, a Z-like path is ideal.
Now let's look at a not so ideal example of reading flow.